Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50011040
TargetCytochrome P450 3A4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544198(CHEMBL4636136)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM207860(US9546153, ex. 35)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM207906(US9546153, ex. 42)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544205(CHEMBL4641090)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM210300(US9546153, ex. 367)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM207894(US9546153, ex. 41)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM206648(US9546153, ex. 8)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM209623(US9546153, ex. 171)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM209595(US9546153, ex. 143)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM210150(US9546153, ex. 286)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544198(CHEMBL4636136)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544201(CHEMBL4632511)
Affinity DataIC50: 7nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544205(CHEMBL4641090)
Affinity DataIC50: 8nMAssay Description:Inhibition of human wild type partial length TNIK (D4-K311 residues) expressed in bacterial expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544204(CHEMBL4643371)
Affinity DataIC50: 8nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM207921(US9546153, ex. 45)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM210298(US9546153, ex. 366)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM206673(US9546153, ex. 9)
Affinity DataIC50: 10nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50262366(CHEMBL4079743)
Affinity DataIC50: 11nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544200(CHEMBL4644871)
Affinity DataIC50: 12nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544199(CHEMBL4639599)
Affinity DataIC50: 15nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544203(CHEMBL4647594)
Affinity DataIC50: 19nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544197(CHEMBL4633251)
Affinity DataIC50: 21nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544202(CHEMBL4648225)
Affinity DataIC50: 24nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544205(CHEMBL4641090)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human cKit (544 to end residues) expressed in baculovirus infected Sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544205(CHEMBL4641090)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM210300(US9546153, ex. 367)
Affinity DataIC50: 130nMAssay Description:Inhibition of human wild type partial length TNIK (D4-K311 residues) expressed in bacterial expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544205(CHEMBL4641090)
Affinity DataIC50: 170nMAssay Description:Inhibition of cKit (unknown origin) by functional based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544205(CHEMBL4641090)
Affinity DataIC50: 190nMAssay Description:Inhibition of human wild type partial length TAK1 (1 to 303 residues) expressed in mammalian expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM207921(US9546153, ex. 45)
Affinity DataIC50: 210nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM207906(US9546153, ex. 42)
Affinity DataIC50: 230nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Mouse)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM207906(US9546153, ex. 42)
Affinity DataIC50: 240nMAssay Description:Inhibition of IRAK4 in mouse whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM206673(US9546153, ex. 9)
Affinity DataIC50: 290nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM206648(US9546153, ex. 8)
Affinity DataIC50: 290nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM209595(US9546153, ex. 143)
Affinity DataIC50: 300nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM207894(US9546153, ex. 41)
Affinity DataIC50: 320nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM50544205(CHEMBL4641090)
Affinity DataIC50: 340nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM210300(US9546153, ex. 367)
Affinity DataIC50: 370nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM210150(US9546153, ex. 286)
Affinity DataIC50: 410nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM207860(US9546153, ex. 35)
Affinity DataIC50: 480nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM209623(US9546153, ex. 171)
Affinity DataIC50: 570nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM207921(US9546153, ex. 45)
Affinity DataIC50: 640nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM210150(US9546153, ex. 286)
Affinity DataIC50: 650nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM210298(US9546153, ex. 366)
Affinity DataIC50: 730nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM210300(US9546153, ex. 367)
Affinity DataIC50: 760nMAssay Description:Inhibition of human wild type partial length IRAK3 (147 to 596 residues) expressed in bacterial expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM207906(US9546153, ex. 42)
Affinity DataIC50: 810nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM206673(US9546153, ex. 9)
Affinity DataIC50: 900nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM210300(US9546153, ex. 367)
Affinity DataIC50: 920nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase receptor TYRO3(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM210300(US9546153, ex. 367)
Affinity DataIC50: 980nMAssay Description:Inhibition of human wild type partial length TYRO3 (497 to 814 residues) expressed in bacterial expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM206648(US9546153, ex. 8)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL
LigandPNGBDBM207894(US9546153, ex. 41)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
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