Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50012752
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50030477(CHEBI:77317 | SR-12813 | CHEMBL458767)
Affinity DataEC50:  1.10E+3nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50541163(CHEMBL4639024)
Affinity DataEC50:  876nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559939(CHEMBL4756373)
Affinity DataEC50:  153nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559940(CHEMBL4761385)
Affinity DataEC50:  417nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559941(CHEMBL4741940)
Affinity DataEC50:  1.16E+3nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559942(CHEMBL4760244)
Affinity DataEC50:  2.77E+3nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559943(CHEMBL4062898)
Affinity DataEC50:  1.34E+3nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559944(CHEMBL4800468)
Affinity DataEC50:  317nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559945(CHEMBL4764757)
Affinity DataEC50:  1.46E+3nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559946(CHEMBL4763395)
Affinity DataEC50:  3.54E+3nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559947(CHEMBL4781362)
Affinity DataEC50:  1.66E+3nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559948(CHEMBL4797059)
Affinity DataEC50:  633nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559949(CHEMBL4750834)
Affinity DataEC50:  795nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed