Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50010785
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542062(CHEMBL4634494)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as increase in beta-arrestin recruitment incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542063(CHEMBL4641283)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as increase in beta-arrestin recruitment incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542064(CHEMBL4634750)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as increase in beta-arrestin recruitment incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as increase in beta-arrestin recruitment incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataIC50: 622nMAssay Description:Antagonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as reduction in beta-arrestin recruitment incubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataIC50: 631nMAssay Description:Antagonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as reduction in beta-arrestin recruitment incubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR4 receptor expressed in Jurkat cells incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataKi:  597nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataKi:  603nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542064(CHEMBL4634750)
Affinity DataKi:  4.09E+3nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542064(CHEMBL4634750)
Affinity DataKi:  4.17E+3nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542063(CHEMBL4641283)
Affinity DataKi:  6.54E+3nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542063(CHEMBL4641283)
Affinity DataKi:  6.61E+3nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542062(CHEMBL4634494)
Affinity DataKi:  1.17E+4nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542062(CHEMBL4634494)
Affinity DataKi:  1.18E+4nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed