Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50010987
TargetDNA topoisomerase 2-alpha(Human)
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 940nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543963(CHEMBL4636680)
Affinity DataIC50: 980nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543962(CHEMBL4642846)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543960(CHEMBL4633308)
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543961(CHEMBL4647427)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543958(CHEMBL4643603)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543959(CHEMBL4636706)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed