Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50018742
TargetTyrosine-protein kinase JAK3(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50611998(CHEMBL5267576)
Affinity DataIC50: 9nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50138474((1R,3R,5S)-3-Benzo[b]thiophen-3-yl-8-((S)-8-methox...)
Affinity DataIC50: 36nMAssay Description:Displacement of [35S] GTPgammaS from human 5-HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50611997(CHEMBL5270978)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50611997(CHEMBL5270978)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50138474((1R,3R,5S)-3-Benzo[b]thiophen-3-yl-8-((S)-8-methox...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [35S] GTPgammaS from human 5-HT1A assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed