Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50010859
TargetEnvelope glycoprotein(ZEBOV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM58492(2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]...)
Affinity DataEC50:  63nMAssay Description:Inhibition of HIV/EBOV GP Y517S mutant infected in 293T cells assessed as reduction in virus entryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnvelope glycoprotein(ZEBOV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM58492(2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]...)
Affinity DataEC50:  63nMAssay Description:Inhibition of HIV/EBOV GP T519V mutant infected in 293T cells assessed as reduction in virus entryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 2C9(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50542718(CHEMBL4647732)
Affinity DataIC50: 3.14E+3nMAssay Description:Inhibition of recombinant human CYP2C9 expressed in baculovirus infected insect cell microsomes using fluorescent substrate in presence of NADPH by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50542713(CHEMBL4634276)
Affinity DataIC50: 4.49E+3nMAssay Description:Inhibition of recombinant human CYP2C9 expressed in baculovirus infected insect cell microsomes using vivid BOMF as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50542716(CHEMBL4638872)
Affinity DataIC50: 4.98E+3nMAssay Description:Inhibition of recombinant human CYP2C9 expressed in baculovirus infected insect cell microsomes using fluorescent substrate in presence of NADPH by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50542717(CHEMBL4640931)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of recombinant human CYP2C9 expressed in baculovirus infected insect cell microsomes using vivid BOMF as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50542713(CHEMBL4634276)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in baculovirus infected insect cell microsomes using vivid DBOMF as substrate preincubated for 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50542714(CHEMBL4640955)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of recombinant human CYP2C9 expressed in baculovirus infected insect cell microsomes using vivid BOMF as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50542717(CHEMBL4640931)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in baculovirus infected insect cell microsomes using vivid DBOMF as substrate preincubated for 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50542714(CHEMBL4640955)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in baculovirus infected insect cell microsomes using vivid DBOMF as substrate preincubated for 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50542715(CHEMBL4644544)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in baculovirus infected insect cell microsomes using vivid DBOMF as substrate preincubated for 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50542715(CHEMBL4644544)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human CYP2C9 expressed in baculovirus infected insect cell microsomes using vivid BOMF as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50542716(CHEMBL4638872)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in baculovirus infected insect cell microsomes using fluorescent substrate in presence of NADPH by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50542718(CHEMBL4647732)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in baculovirus infected insect cell microsomes using fluorescent substrate in presence of NADPH by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed