Compile Data Set for Download or QSAR
Report error Found 77 Enz. Inhib. hit(s) with all data for entry = 50018489
TargetBifunctional epoxide hydrolase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50217448(trans-4-[4-(3-adamantan-1-ylureido)cyclohexyloxy]b...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant sEHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608695(CHEMBL5277674)
Affinity DataIC50: 17nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608685(CHEMBL5277627)
Affinity DataIC50: 42nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608694(CHEMBL5266412)
Affinity DataIC50: 44nMAssay Description:Inhibition of ovine COX-1 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608693(CHEMBL5274548)
Affinity DataIC50: 46nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608692(CHEMBL5288685)
Affinity DataIC50: 48nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 70nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608681(CHEMBL5290910)
Affinity DataIC50: 70nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608695(CHEMBL5277674)
Affinity DataIC50: 75nMAssay Description:Inhibition of ovine COX-1 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608676(CHEMBL5270639)
Affinity DataIC50: 100nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608699(CHEMBL5274157)
Affinity DataIC50: 100nMAssay Description:Inhibition of human COX-2 assessed as by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608682(CHEMBL5266991)
Affinity DataIC50: 110nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608704(CHEMBL5283786)
Affinity DataIC50: 110nMAssay Description:Inhibition of COX-2 (unknown origin) assessed as inhibition at 15 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608683(CHEMBL5288527)
Affinity DataIC50: 120nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608705(CHEMBL5283831)
Affinity DataIC50: 150nMAssay Description:Inhibition of COX-2 (unknown origin) assessed as inhibition at 15 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608700(CHEMBL5266680)
Affinity DataIC50: 160nMAssay Description:Inhibition of human COX-2 assessed as by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608684(CHEMBL5287285)
Affinity DataIC50: 170nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 200nMAssay Description:Inhibition of COX-1 (unknown origin) at 40 uM relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 300nMAssay Description:Inhibition of COX-2 (unknown origin) at 0.5 uM by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608680(CHEMBL5282224)
Affinity DataIC50: 320nMAssay Description:Inhibition of 5-LOX (unknown origin) after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608701(CHEMBL5275735)
Affinity DataIC50: 370nMAssay Description:Inhibition of COX-2 (unknown origin) assessed as inhibition at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608690(CHEMBL5282220)
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608689(CHEMBL5288634)
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608694(CHEMBL5266412)
Affinity DataIC50: 452nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 490nMAssay Description:Inhibition of COX-2 (unknown origin) assessed as inhibition at 15 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 510nMAssay Description:Inhibition of ovine COX-1 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608688(CHEMBL5271889)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608707(CHEMBL5285524)
Affinity DataIC50: 540nMAssay Description:Inhibition of COX-2 (unknown origin) at 0.5 uM by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608675(CHEMBL5276174)
Affinity DataIC50: 540nMAssay Description:Inhibition of COX-2 (unknown origin) at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608686(CHEMBL5284488)
Affinity DataIC50: 560nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608697(CHEMBL5270605)
Affinity DataIC50: 580nMAssay Description:Inhibition of COX-2 (unknown origin) by EIA kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608687(CHEMBL5271850)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608696(CHEMBL5268949)
Affinity DataIC50: 670nMAssay Description:Inhibition of COX-2 (unknown origin) by EIA kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608706(CHEMBL5273441)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant sEHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 780nMAssay Description:Inhibition of COX-2 (unknown origin) at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608701(CHEMBL5275735)
Affinity DataIC50: 780nMAssay Description:Inhibition of COX-2 (unknown origin) at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 840nMAssay Description:Inhibition of ovine COX-1 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608674(CHEMBL5279915)
Affinity DataIC50: 870nMAssay Description:Inhibition of COX-2 (unknown origin) at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 870nMAssay Description:Inhibition of COX-2 (unknown origin) by EIA kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608698(CHEMBL5270009)
Affinity DataIC50: 900nMAssay Description:Inhibition of 5-LOX (unknown origin) after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM27684(2-(4-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxam...)
Affinity DataIC50: 980nMAssay Description:Inhibition of ovine COX-1 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608680(CHEMBL5282224)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608680(CHEMBL5282224)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of 15-LOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of COX-2 (unknown origin) at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608703(CHEMBL5288533)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of COX-2 (unknown origin) at 5 uM by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608696(CHEMBL5268949)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608697(CHEMBL5270605)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608691(CHEMBL5267677)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of COX-1 (unknown origin) at 40 uM relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
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