Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 50011297
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509750(CHEMBL4439327)
Affinity DataIC50: 35nMAssay Description:Inhibition of human AKR1C3 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546234(CHEMBL4758386)
Affinity DataIC50: 53nMAssay Description:Inhibition of human AKR1C3 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546235(CHEMBL4795494)
Affinity DataIC50: 82nMAssay Description:Inhibition of human AKR1C3 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50382163(CHEMBL2023820)
Affinity DataIC50: 86nMAssay Description:Inhibition of human AKR1C3 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: 230nMAssay Description:Inhibition of AKR1C3 (unknown origin) expressed in human HCT116 cells incubated for 3 to 6 hrs by UHPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509767(CHEMBL4513510)
Affinity DataIC50: 290nMAssay Description:Inhibition of human AKR1C3 using 4-AD as substrate in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 390nMAssay Description:Inhibition of N-terminal His-tagged human AKR1B10 expressed in Escherichia coli BL21 (Condon Plus) competent cells using pyridine-3-aldehydenone as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546238(CHEMBL267484)
Affinity DataIC50: 690nMAssay Description:Inhibition of human AKR1C3 expressed in Escherichia coli BL21(DE3) pLysS cells using S-tetralol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM22231(CHEMBL267476 | (9Z,12Z)-octadeca-9,12-dienoic acid...)
Affinity DataIC50: 690nMAssay Description:Inhibition of human AKR1C3 expressed in Escherichia coli BL21(DE3) pLysS cells using 9,10-phenanthrenequinone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM22231(CHEMBL267476 | (9Z,12Z)-octadeca-9,12-dienoic acid...)
Affinity DataIC50: 690nMAssay Description:Inhibition of human AKR1C3 expressed in Escherichia coli BL21(DE3) pLysS cells using S-tetralol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546238(CHEMBL267484)
Affinity DataIC50: 840nMAssay Description:Inhibition of human AKR1C3 expressed in Escherichia coli BL21(DE3) pLysS cells using 9,10-phenanthrenequinone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237590(CHEBI:5383 | Amaryl | Glimepiride | HOE-490 | Nidd...)
Affinity DataIC50: 850nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C3 expressed in Escherichia coli BL21(Condon Plus) competent cells using 9,10-phenanthrenequinone as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509750(CHEMBL4439327)
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity at androgen receptor (unknown origin) expressed in human HeLa cells harboring AR3A-PSA-(ARE)4-Luc13 in presence of DHT by BrightG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7585(2,6,9-Trisubstituted purine deriv. 27 | CHEMBL5238...)
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of human AKR1C3 expressed in Escherichia coli incubated for 30 mins in presence of NADPH regeneration system by UHPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of AKR1C3 (unknown origin) using 9,10-phenanthrenequinone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240376(n-octylgallate | 3,4,5-Trihydroxy-benzoic acid oct...)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C3 expressed in Escherichia coli BL21 (Condon Plus) competent cells using 9,10 -Phenanthrenequinone as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 3.56E+3nMAssay Description:Inhibition of N-terminal His-tagged human AKR1B1 expressed in Escherichia coli BL21 (Condon Plus) competent cells using D,L-glyceraldehyde as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C3 expressed in Escherichia coli BL21 (Condon Plus) competent cells using 9,10 -Phenanthrenequinone as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240376(n-octylgallate | 3,4,5-Trihydroxy-benzoic acid oct...)
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C4 expressed in Escherichia coli BL21 (Condon Plus) competent cells using 9,10 -Phenanthrenequinone as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 4.08E+3nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C3 (1 to 323 residues) expressed in Escherichia coli using 4-adione as substrate in presence of NADPH b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546234(CHEMBL4758386)
Affinity DataIC50: 5.34E+3nMAssay Description:Inhibition of human AKR1C4 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240376(n-octylgallate | 3,4,5-Trihydroxy-benzoic acid oct...)
Affinity DataIC50: 5.48E+3nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C1 expressed in Escherichia coli BL21 (Condon Plus) competent cells using 9,10 -Phenanthrenequinone as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546239(CHEMBL103579)
Affinity DataIC50: 6.58E+3nMAssay Description:Inhibition of human AKR1C3 expressed in Escherichia coli incubated for 30 mins in presence of NADPH regeneration system by UHPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237590(CHEBI:5383 | Amaryl | Glimepiride | HOE-490 | Nidd...)
Affinity DataIC50: 6.86E+3nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C1 expressed in Escherichia coli BL21 (Condon Plus) competent cells using 9,10-phenanthrenequinone as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 7.26E+3nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C3 (1 to 323 residues) expressed in Escherichia coli using 4-adione as substrate in presence of NADPH b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546236(CHEMBL4742775)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of AKR1C3 (unknown origin) using 9,10-phenanthrenequinone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of AKR1C3 (unknown origin) expressed in human HCT116 cells incubated for 2 to 4 hrs by UHPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50382163(CHEMBL2023820)
Affinity DataIC50: 8.00E+3nMAssay Description:Displacement of [3H]-R1881 from androgen receptor (unknown origin) expressed in human HeLa cells harboring AR3A-PSA-(ARE)4-Luc13 incubated for 2 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 8.25E+3nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C4 expressed in Escherichia coli BL21 (Condon Plus) competent cells using 9,10 -Phenanthrenequinone as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240376(n-octylgallate | 3,4,5-Trihydroxy-benzoic acid oct...)
Affinity DataIC50: 9.28E+3nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C2 expressed in Escherichia coli BL21 (Condon Plus) competent cells using 9,10 -Phenanthrenequinone as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human AKR1C3 expressed in Escherichia coli incubated for 30 mins in presence of NADPH regeneration system by UHPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546236(CHEMBL4742775)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of AKR1C3 (unknown origin) using 4-androstene-3,17-dione as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546234(CHEMBL4758386)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of human AKR1C1 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546234(CHEMBL4758386)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of human AKR1C2 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546237(TAZETTINE | CHEBI:32185 | (+)-Tazettine)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human AKR1C3 expressed in Escherichia coli preincubated for 15 mins followed by Adion addition and measured after 30 mins by HPLC analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546235(CHEMBL4795494)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of human AKR1C4 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546235(CHEMBL4795494)
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of human AKR1C2 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50103512(CHEBI:31654 | Gliclazide | SE-1702)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C3 expressed in Escherichia coli BL21(Condon Plus) competent cells using 9,10-phenanthrenequinone as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50382163(CHEMBL2023820)
Affinity DataIC50: 2.10E+4nMAssay Description:Antagonist activity at androgen receptor (unknown origin) expressed in human HeLa cells harboring AR3A-PSA-(ARE)4-Luc13 in presence of DHT by BrightG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50382163(CHEMBL2023820)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of human AKR1C2 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 2.58E+4nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C2 expressed in Escherichia coli BL21 (Condon Plus) competent cells using 9,10 -Phenanthrenequinone as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 2.92E+4nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C1 expressed in Escherichia coli BL21 (Condon Plus) competent cells using 9,10 -Phenanthrenequinone as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50382163(CHEMBL2023820)
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of human AKR1C4 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50382163(CHEMBL2023820)
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of human AKR1C1 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237590(CHEBI:5383 | Amaryl | Glimepiride | HOE-490 | Nidd...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His-tagged human AKR1C2 expressed in Escherichia coli BL21 (Condon Plus) competent cells using 9,10-phenanthrenequinone as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546235(CHEMBL4795494)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human AKR1C1 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member A1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His-tagged human AKR1A1 expressed in Escherichia coli BL21 (Condon Plus) competent cells using D,L-glyceraldehyde as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AKR1C2 (unknown origin) using 9,10-phenanthrenequinone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546236(CHEMBL4742775)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human COX-2 expressed in Sf9 insect cells using [14C] arachidonic acid as substrate preincubated for 20 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50546236(CHEMBL4742775)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of ovine COX-1 using [14C] arachidonic acid as substrate preincubated for 20 mins followed by substrate addition measured after 30 sec by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
Displayed 1 to 50 (of 63 total ) | Next | Last >>
Jump to: