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Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50010599
TargetMonoglyceride lipase(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50: 0.219nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50065646(CHEMBL3087181)
Affinity DataIC50: 0.275nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US9133148, A | US11753371, Compound...)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540526(CHEMBL4637658)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50414921(CHEMBL570812)
Affinity DataIC50: 86nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50414921(CHEMBL570812)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50450776(CHEMBL4203881)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50393668(CHEMBL2158989)
Affinity DataIC50: 155nMAssay Description:Inhibition of human MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50307083(4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carb...)
Affinity DataIC50: 205nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540536(CHEMBL1899736)
Affinity DataIC50: 333nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540542(CHEMBL4639080)
Affinity DataIC50: 576nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540539(CHEMBL4645190)
Affinity DataIC50: 662nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540537(CHEMBL4640805)
Affinity DataIC50: 926nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540541(CHEMBL4633542)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50393668(CHEMBL2158989)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540531(CHEMBL4634010)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540543(CHEMBL4643556)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540545(CHEMBL4633674)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540528(CHEMBL4635137)
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540529(CHEMBL4649426)
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540530(CHEMBL4648677)
Affinity DataIC50: 4.03E+3nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540544(CHEMBL4640502)
Affinity DataIC50: 4.07E+3nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540527(CHEMBL4632950)
Affinity DataIC50: 7.33E+3nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540534(CHEMBL4640057)
Affinity DataIC50: 9.92E+3nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540526(CHEMBL4637658)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CB2 receptor (unknown origin) expressed in Flpin-CHO cells incubated for 10 mins by Eu-cAMP tracer based cAMP accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540526(CHEMBL4637658)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CB1 receptor (unknown origin) expressed in Flpin-CHO cells incubated for 10 mins by Eu-cAMP tracer based cAMP accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540540(CHEMBL4636309)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540532(CHEMBL4637837)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540538(CHEMBL4648834)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540535(CHEMBL4643507)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540533(CHEMBL4646803)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540526(CHEMBL4637658)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant FAAH pre-incubated for 5 mins before substrate addition and further incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540546(CHEMBL4638760)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540547(CHEMBL4645591)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540548(CHEMBL4633147)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540549(CHEMBL4646896)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540550(CHEMBL4644232)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540526(CHEMBL4637658)
Affinity DataKi:  13nMAssay Description:Competitive inhibition of human recombinant MAGL at 31.25 nM to 125 nM pre-incubated for 5 mins before MAGL substrate addition and further incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed