Compile Data Set for Download or QSAR
Report error Found 70 Enz. Inhib. hit(s) with all data for entry = 50013311
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM25870(CITALOPRAM HYDROBROMIDE | [3H]Escitalopram | Escit...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564642(CHEMBL4777782)
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564637(CHEMBL4786060)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564636(CHEMBL4782029)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564635(CHEMBL4795221)
Affinity DataIC50: 9.20E+3nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564634(CHEMBL4800092)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564638(CHEMBL4781245)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564639(CHEMBL4776389)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564631(CHEMBL4790454)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564633(CHEMBL4796328)
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564629(CHEMBL4798408)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564623(CHEMBL4782574)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564625(CHEMBL4782256)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564627(CHEMBL4786386)
Affinity DataIC50: 3.24E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564642(CHEMBL4777782)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564622(CHEMBL4789608)
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564624(CHEMBL4800589)
Affinity DataIC50: 3.57E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564652(CHEMBL4783315)
Affinity DataIC50: 3.73E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564640(CHEMBL4786300)
Affinity DataIC50: 3.73E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564626(CHEMBL4784248)
Affinity DataIC50: 3.94E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564635(CHEMBL4795221)
Affinity DataIC50: 3.94E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564653(CHEMBL4778249)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564621(CHEMBL4793718)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564641(CHEMBL4798858)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564651(CHEMBL4785452)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564650(CHEMBL4799265)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564649(CHEMBL4780560)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564648(CHEMBL4792702)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564647(CHEMBL4788937)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564646(CHEMBL4785035)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564645(CHEMBL4786778)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564644(CHEMBL4796660)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564643(CHEMBL4798281)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564632(CHEMBL4797232)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564630(CHEMBL4780578)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564628(CHEMBL4792068)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564641(CHEMBL4798858)
Affinity DataIC50: 6.90E+4nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM25870(CITALOPRAM HYDROBROMIDE | [3H]Escitalopram | Escit...)
Affinity DataIC50: 7.33E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564639(CHEMBL4776389)
Affinity DataIC50: 8.30E+4nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564636(CHEMBL4782029)
Affinity DataIC50: 1.22E+5nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564634(CHEMBL4800092)
Affinity DataIC50: 1.33E+5nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564638(CHEMBL4781245)
Affinity DataIC50: 1.49E+5nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564640(CHEMBL4786300)
Affinity DataIC50: 1.81E+5nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564637(CHEMBL4786060)
Affinity DataIC50: 2.12E+5nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564632(CHEMBL4797232)
Affinity DataIC50: 3.20E+5nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564633(CHEMBL4796328)
Affinity DataIC50: 5.46E+5nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564653(CHEMBL4778249)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564651(CHEMBL4785452)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564652(CHEMBL4783315)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
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