Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50010855
TargetKappa-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50264567(CHEMBL4063074)
Affinity DataIC50: 7.70nMAssay Description:Antagonist activity at human kappa opiod receptor expressed in CHO cells assessed as inhibition of U69593-induced [35S]GTPgammaS binding incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50264567(CHEMBL4063074)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human mu opiod receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding incubated for 4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50264567(CHEMBL4063074)
Affinity DataIC50: 109nMAssay Description:Antagonist activity at human delta opiod receptor expressed in human HEK293 cells assessed as inhibition of DPDPE-induced [35S]GTPgammaS binding incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)
Affinity DataIC50: 178nMAssay Description:Antagonist activity at human kappa opiod receptor expressed in CHO cells assessed as inhibition of U69593-induced [35S]GTPgammaS binding incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)
Affinity DataIC50: 202nMAssay Description:Antagonist activity at human mu opiod receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding incubated for 4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at human delta opiod receptor expressed in human HEK293 cells assessed as inhibition of DPDPE-induced [35S]GTPgammaS binding incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50264567(CHEMBL4063074)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50264567(CHEMBL4063074)
Affinity DataKi:  94nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50264567(CHEMBL4063074)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]-DPDPE from human delta opiod receptor expressed in human HEK293 cells incubated for 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542606(CHEMBL4636535)
Affinity DataKi:  498nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542608(CHEMBL4638966)
Affinity DataKi:  1.41E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542608(CHEMBL4638966)
Affinity DataKi:  1.48E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542607(CHEMBL4644052)
Affinity DataKi:  2.15E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)
Affinity DataKi:  2.31E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542606(CHEMBL4636535)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542607(CHEMBL4644052)
Affinity DataKi:  4.76E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542608(CHEMBL4638966)
Affinity DataKi:  5.01E+3nMAssay Description:Displacement of [3H]-DPDPE from human delta opiod receptor expressed in human HEK293 cells incubated for 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542607(CHEMBL4644052)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DPDPE from human delta opiod receptor expressed in human HEK293 cells incubated for 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542606(CHEMBL4636535)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DPDPE from human delta opiod receptor expressed in human HEK293 cells incubated for 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50542605(CHEMBL4648915)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DPDPE from human delta opiod receptor expressed in human HEK293 cells incubated for 60 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed