Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50013300
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 46nMAssay Description:Inhibition of EGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 95nMAssay Description:Inhibition of EGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564477(CHEMBL4779958)
Affinity DataIC50: 358nMAssay Description:Inhibition of EGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564478(CHEMBL4782320)
Affinity DataIC50: 493nMAssay Description:Inhibition of EGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564480(CHEMBL4789796)
Affinity DataIC50: 993nMAssay Description:Inhibition of EGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564475(CHEMBL4799700)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of EGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564476(CHEMBL4778717)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of EGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564479(CHEMBL4776925)
Affinity DataIC50: 8.26E+3nMAssay Description:Inhibition of EGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 6.11E+4nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564477(CHEMBL4779958)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 9.20E+4nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564478(CHEMBL4782320)
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 3.77E+5nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 4.21E+5nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564477(CHEMBL4779958)
Affinity DataIC50: 4.33E+5nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564478(CHEMBL4782320)
Affinity DataIC50: 4.62E+5nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed