Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50007707
TargetHistone deacetylase 6(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 24nMAssay Description:Inhibition of HDAC6 (unknown origin) after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 56nMAssay Description:Inhibition of HDAC1 (unknown origin) after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50511920(CHEMBL4546176)
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC6 (unknown origin) after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50511920(CHEMBL4546176)
Affinity DataIC50: 280nMAssay Description:Inhibition of HDAC1 (unknown origin) after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50511919(CHEMBL4562449)
Affinity DataIC50: 600nMAssay Description:Inhibition of HDAC6 (unknown origin) after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50511919(CHEMBL4562449)
Affinity DataIC50: 690nMAssay Description:Inhibition of HDAC1 (unknown origin) after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 850nMAssay Description:Inhibition of HDAC in HUVEC using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition and measured after 4 hrs by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50511919(CHEMBL4562449)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of HDAC in HUVEC using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition and measured after 4 hrs by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50511920(CHEMBL4546176)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of HDAC in HUVEC using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition and measured after 4 hrs by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM25817(Fungata | Diflucan | Fluconazole (f) | cid_3365 | ...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of HDAC in HUVEC using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition and measured after 4 hrs by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed