Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50010409
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538595BDBM50538595(CHEMBL4645086)
Affinity DataEC50:  37nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as concentration required to show half of DOX IC50 incubated for 48 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538601BDBM50538601(CHEMBL4649501)
Affinity DataEC50:  51nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as concentration required to show half of DOX IC50 incubated for 48 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538591BDBM50538591(CHEMBL4648775)
Affinity DataEC50:  103nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as concentration required to show half of DOX IC50 incubated for 48 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538591BDBM50538591(CHEMBL4648775)
Affinity DataIC50: 390nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538602BDBM50538602(CHEMBL4641044)
Affinity DataIC50: 490nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538586BDBM50538586(CHEMBL4637550)
Affinity DataIC50: 550nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538589BDBM50538589(CHEMBL4634549)
Affinity DataIC50: 550nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538595BDBM50538595(CHEMBL4645086)
Affinity DataIC50: 560nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538601BDBM50538601(CHEMBL4649501)
Affinity DataIC50: 610nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538600BDBM50538600(CHEMBL4642247)
Affinity DataIC50: 700nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538594BDBM50538594(CHEMBL4635941)
Affinity DataIC50: 740nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538592BDBM50538592(CHEMBL4646045)
Affinity DataIC50: 750nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538599BDBM50538599(CHEMBL4637515)
Affinity DataIC50: 760nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538593BDBM50538593(CHEMBL4634981)
Affinity DataIC50: 760nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538597BDBM50538597(CHEMBL4647036)
Affinity DataIC50: 780nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538584BDBM50538584(CHEMBL4643278)
Affinity DataIC50: 820nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538596BDBM50538596(CHEMBL4637809)
Affinity DataIC50: 820nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538590BDBM50538590(CHEMBL4641589)
Affinity DataIC50: 990nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538585BDBM50538585(CHEMBL4641324)
Affinity DataIC50: 1.10E+3nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538598BDBM50538598(CHEMBL4634027)
Affinity DataIC50: 1.18E+3nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538587BDBM50538587(CHEMBL4634838)
Affinity DataIC50: 1.36E+3nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538588BDBM50538588(CHEMBL4642196)
Affinity DataIC50: 1.97E+3nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81939BDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 2.98E+3nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed