Compile Data Set for Download or QSAR
Report error Found 79 Enz. Inhib. hit(s) with all data for entry = 50010586
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521419BDBM50521419(CHEMBL1342201)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540386BDBM50540386(CHEMBL4647644 | US11427590, Entry 44 | US202401155...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540407BDBM50540407(CHEMBL4646734)
Affinity DataIC50: 70nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540378BDBM50540378(CHEMBL4634085 | US11427590, Entry 22 | US202401155...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540383BDBM50540383(CHEMBL4635273 | US11427590, Entry 25 | US202401155...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540366BDBM50540366(CHEMBL4635335 | US11427590, Entry 37 | US202401155...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540363BDBM50540363(CHEMBL4643888 | US11427590, Entry 32 | US202401155...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540376BDBM50540376(CHEMBL4644091 | US11427590, Entry 24 | US202401155...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540356BDBM50540356(CHEMBL4632464 | US11427590, Entry 17 | US202401155...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540372BDBM50540372(CHEMBL4648184 | US11427590, Entry 42 | US202401155...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540369BDBM50540369(CHEMBL4632713 | US11427590, Entry 19 | US202401155...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540384BDBM50540384(CHEMBL4644595)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540382BDBM50540382(CHEMBL4640034 | US11427590, Entry 23 | US202401155...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540349BDBM50540349(CHEMBL4648675 | US11427590, Entry 9 | US2024011557...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540365BDBM50540365(CHEMBL4633254 | US11427590, Entry 34 | US202401155...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540381BDBM50540381(CHEMBL4632415 | US11427590, Entry 30 | US202401155...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540371BDBM50540371(CHEMBL4646637 | US11427590, Entry 41 | US202401155...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540370BDBM50540370(CHEMBL4639494 | US11427590, Entry 39 | US202401155...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540385BDBM50540385(CHEMBL4649470 | US11427590, Entry 26 | US202401155...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540352BDBM50540352(CHEMBL4643164 | US11427590, Entry 13 | US202401155...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540397BDBM50540397(CHEMBL4639393 | US11427590, Entry 59 | US202401155...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540395BDBM50540395(CHEMBL4648122 | US11427590, Entry 56 | US202401155...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540359BDBM50540359(CHEMBL4647717)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540375BDBM50540375(CHEMBL4644815 | US11427590, Entry 27 | US202401155...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540358BDBM50540358(CHEMBL4647138 | US11427590, Entry 38 | US202401155...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540373BDBM50540373(CHEMBL4645128 | US11427590, Entry 43 | US202401155...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540399BDBM50540399(CHEMBL4646175 | US11427590, Entry 60 | US202401155...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540367BDBM50540367(CHEMBL4645484 | US11427590, Entry 36 | US202401155...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540364BDBM50540364(CHEMBL4636705 | US11427590, Entry 33 | US202401155...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540380BDBM50540380(CHEMBL4647259 | US11427590, Entry 29 | US202401155...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540351BDBM50540351(CHEMBL4635005 | US11427590, Entry 11 | US202401155...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540350BDBM50540350(CHEMBL4643840 | US11427590, Entry 10 | US202401155...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540393BDBM50540393(CHEMBL4645616 | US11427590, Entry 52 | US202401155...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540377BDBM50540377(CHEMBL4640489 | US11427590, Entry 28 | US202401155...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540348BDBM50540348(CHEMBL4634886 | US11427590, Entry 7 | US2024011557...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540361BDBM50540361(CHEMBL4640369 | US11427590, Entry 43-PROV | US2024...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540392BDBM50540392(CHEMBL4649016 | US11427590, Entry 51 | US202401155...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540398BDBM50540398(CHEMBL4646834 | US11427590, Entry 57 | US202401155...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540396BDBM50540396(CHEMBL4643224 | US11427590, Entry 58 | US202401155...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540345BDBM50540345(CHEMBL4637377)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540390BDBM50540390(CHEMBL4642381 | US11427590, Entry 49 | US202401155...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540357BDBM50540357(CHEMBL4648938 | US11427590, Entry 18 | US202401155...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540355BDBM50540355(CHEMBL4639208 | US11427590, Entry 16 | US202401155...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540368BDBM50540368(CHEMBL4649186 | US11427590, Entry 39b-PROV | US202...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540353BDBM50540353(CHEMBL4633305 | US11427590, Entry 14 | US202401155...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540394BDBM50540394(CHEMBL4637546 | US11427590, Entry 53 | US202401155...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540362BDBM50540362(CHEMBL4649068 | US11427590, Entry 35 | US202401155...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540405BDBM50540405(CHEMBL4636748 | US11427590, Entry 61 | US202401155...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540337BDBM50540337(CHEMBL4638718 | US11427590, Entry 1 | US2024011557...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29040BDBM29040(cambinol)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
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