Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50010732
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522755BDBM50522755(CHEMBL4528755)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391109BDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522762BDBM50522762(CHEMBL4475087)
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522758BDBM50522758(CHEMBL4473832)
Affinity DataIC50: 2.62E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522753BDBM50522753(CHEMBL4514758)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522757BDBM50522757(CHEMBL4458937)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522754BDBM50522754(CHEMBL4453336)
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522761BDBM50522761(CHEMBL4465327)
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522760BDBM50522760(CHEMBL4471983)
Affinity DataIC50: 7.69E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522759BDBM50522759(CHEMBL4461708)
Affinity DataIC50: 8.27E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522756BDBM50522756(CHEMBL4532631)
Affinity DataIC50: 9.85E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed