Report error Found 135 Enz. Inhib. hit(s) with all data for entry = 50010392
Affinity DataKd: 6.5nMAssay Description:Binding affinity to human muscarinic M1 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
Affinity DataKd: 2.60nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
Affinity DataKd: 0.891nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
Affinity DataKd: 4.5nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
Affinity DataKd: 0.646nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
Affinity DataKd: 9.5nMAssay Description:Binding affinity to human muscarinic M4 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
Affinity DataKd: 26nMAssay Description:Binding affinity to human muscarinic M1 receptor expressed in CHO-K9 cells incubated in dark measured after 60 mins by Hoechst H33342 dye based confo...More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to human muscarinic M1 receptor expressed in CHO-K9 cells incubated in dark measured after 60 mins by Hoechst H33342 dye based confo...More data for this Ligand-Target Pair
Affinity DataKd: 8.70nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark measured after 60 mins by Hoechst H33342 dye based confo...More data for this Ligand-Target Pair
Affinity DataKd: 4.70nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark measured after 60 mins by Hoechst H33342 dye based confo...More data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark measured after 60 mins by Hoechst H33342 dye based confo...More data for this Ligand-Target Pair
Affinity DataKd: 5.60nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark measured after 60 mins by Hoechst H33342 dye based confo...More data for this Ligand-Target Pair
Affinity DataKd: 2.57nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
Affinity DataKd: 0.480nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells at 22 +/- 1 degree C preincubated for 180 mins followed by atropine additi...More data for this Ligand-Target Pair
Affinity DataKd: 1.90nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells at 22 +/- 1 degree C preincubated for 120 mins followed by atropine additi...More data for this Ligand-Target Pair
Affinity DataKd: 1.40nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells at 22 +/- 1 degree C preincubated for 110 mins followed by atropine additi...More data for this Ligand-Target Pair
Affinity DataKd: 0.813nMAssay Description:Displacement of [3H]-UR-SK259 human muscarinic M1 receptorMore data for this Ligand-Target Pair
Affinity DataKd: 794nMAssay Description:Binding affinity to EGFP-fused human muscarinic M1 receptorMore data for this Ligand-Target Pair
Affinity DataKd: 0.891nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
Affinity DataKd: 4.10nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
Affinity DataKd: 3.09nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
Affinity DataKd: 0.650nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark at 22 degree C for 2 hrs by FACSCalibur flow cytometric ...More data for this Ligand-Target Pair
Affinity DataKd: 8.71nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark measured after 60 mins by Hoechst H33342 dye based confo...More data for this Ligand-Target Pair
Affinity DataKd: 4.68nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark measured after 60 mins by Hoechst H33342 dye based confo...More data for this Ligand-Target Pair
Affinity DataKd: 11.5nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark measured after 60 mins by Hoechst H33342 dye based confo...More data for this Ligand-Target Pair
Affinity DataKd: 5.62nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells incubated in dark measured after 60 mins by Hoechst H33342 dye based confo...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human muscarinic M4 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Antagonist activity at human muscarinic M4 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:Antagonist activity at human muscarinic M4 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 138nMAssay Description:Antagonist activity at human muscarinic M4 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 355nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Affinity DataKi: 0.138nMAssay Description:Displacement of 4-(2-((1E,3E)-5-((E)-3,3-Dimethyl-1-(6-oxo-6-((2-(3-(1-(4-(1-(2-oxo-2-(11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-5-yl)ethyl)p...More data for this Ligand-Target Pair
Affinity DataKi: 0.182nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.195nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.257nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.269nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.355nMAssay Description:Displacement of 4-(2-((1E,3E)-5-((E)-3,3-Dimethyl-1-(6-oxo-6-((2-(3-(1-(4-(1-(2-oxo-2-(11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-5-yl)ethyl)p...More data for this Ligand-Target Pair
Affinity DataKi: 0.447nMAssay Description:Displacement of [3H]-NMS from human muscarinic M4 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.525nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.525nMAssay Description:Displacement of 4-(2-((1E,3E)-5-((E)-1-(6-((3,5-Bis((2-(3-(1-(4-(1-(2-oxo-2-(11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-5-yl)ethyl)piperidin-4...More data for this Ligand-Target Pair
Affinity DataKi: 0.589nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
