Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50018473
TargetToll-like receptor 7(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50608583(CHEMBL5275095)
Affinity DataEC50:  1.57E+3nMAssay Description:Agonist activity at TLR-7 (unknown origin) by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 3(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50459216(CHEMBL4213673)
Affinity DataKd:  98nMAssay Description:Binding affinity to ERK1 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50559854(Motolimod | VTX-2337 | VTX-378)
Affinity DataEC50:  100nMAssay Description:Agonist activity at TLR8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50608584(CHEMBL5275885)
Affinity DataEC50:  3.00E+4nMAssay Description:Agonist activity at human TLR8 transfected in HEK-Blue hTLR8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50608584(CHEMBL5275885)
Affinity DataEC50:  1.50E+4nMAssay Description:Agonist activity at human TLR7 transfected in HEK-Blue hTLR7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50608584(CHEMBL5275885)
Affinity DataEC50:  30nMAssay Description:Agonist activity in TLR8 (unknown origin) expressed in HEK293 cells assessed as induction of NF-kappa activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity in TLR8 (unknown origin) expressed in HEK293 cells assessed as induction of NF-kappa activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50398245(CL-075 | CHEMBL512901)
Affinity DataEC50:  800nMAssay Description:Agonist activity in TLR8 (unknown origin) expressed in HEK293 cells assessed as induction of NF-kappa activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50408506(CHEMBL5272163)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human TLR8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  1.50E+3nMAssay Description:Activation of TLR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  4.50E+3nMAssay Description:Activation of TLR8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50552139(CHEMBL4790706)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human TLR8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50608585(CHEMBL5274101)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human TLR8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50587872(CHEMBL4553089)
Affinity DataIC50: 67nMAssay Description:Inhibition of human TLR8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)