Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50010518
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50441629BDBM50441629(LESPEDEZAFLAVANONE B)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442403BDBM50442403(CHEMBL494252)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539739BDBM50539739(CHEMBL3808735)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539738BDBM50539738(CHEMBL4638191)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539737BDBM50539737(CHEMBL4647021)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539740BDBM50539740(CHEMBL3810179)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539735BDBM50539735(CHEMBL4638927)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148911BDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539734BDBM50539734(CHEMBL4639007)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172097BDBM50172097(CHEMBL3809337)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172098BDBM50172098(CHEBI:69082 | Licoricidin)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539732BDBM50539732(CHEMBL4639637)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539733BDBM50539733(CHEMBL4636630)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253187BDBM50253187(CHEMBL3810262)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539736BDBM50539736(CHEMBL4634824)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172094BDBM50172094(CHEMBL3808919)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172093BDBM50172093(CHEMBL3809403)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539741BDBM50539741(CHEMBL4638414)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50213492BDBM50213492(2-[2',4'-dihydroxy-3'-(3-methylbut-2-enyl)phenyl]-...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed