Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50007675
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511523BDBM50511523(CHEMBL4532318)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511530BDBM50511530(CHEMBL4455867)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511534BDBM50511534(CHEMBL4450284)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511532BDBM50511532(CHEMBL4582494)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511525BDBM50511525(CHEMBL4529403)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511531BDBM50511531(CHEMBL4460751)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511522BDBM50511522(CHEMBL4577193)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511526BDBM50511526(CHEMBL4462115)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511520BDBM50511520(CHEMBL4533275)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511524BDBM50511524(CHEMBL4473767)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511535BDBM50511535(CHEMBL4540096)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246436BDBM50246436(CHEMBL4090510)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511521BDBM50511521(CHEMBL4461057)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511529BDBM50511529(CHEMBL4457871)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241949BDBM241949(US9428466, Merbarone)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511527BDBM50511527(CHEMBL4441893)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241949BDBM241949(US9428466, Merbarone)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human topo2alpha by plasmid relaxation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127140BDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataIC50: 4.75E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511528BDBM50511528(CHEMBL4591521)
Affinity DataIC50: 7.44E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511533BDBM50511533(CHEMBL4543031)
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed