Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50007654
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511298(CHEMBL4451058)
Affinity DataEC50:  410nMAssay Description:Inhibition of acid ceramidase in Krabbe's disease patient-derived primary fibroblasts using Rbm14-12 as substrate measured after 2 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511298(CHEMBL4451058)
Affinity DataKon:  0.00250M-1s-1Assay Description:Time-dependent inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511300(CHEMBL4580541)
Affinity DataIC50: 3nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511282(CHEMBL4592427)
Affinity DataIC50: 6nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511276(CHEMBL4461146)
Affinity DataIC50: 24nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511273(CHEMBL4541371)
Affinity DataIC50: 52nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511290(CHEMBL4483813)
Affinity DataIC50: 56nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511280(CHEMBL4515178)
Affinity DataIC50: 60nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511265(CHEMBL4471764)
Affinity DataIC50: 64nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM367184(2-oxo-N-(4-phenylbutyl)-1,3- benzoxazole-3-carboxa...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells preincubated for 30 mins followed by fluorogenic probe addition and measured after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511271(CHEMBL4471752)
Affinity DataIC50: 68nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511298(CHEMBL4451058)
Affinity DataIC50: 70nMAssay Description:Inhibition of human FAAH expressed in HEK293 cells using AMC arachidonyl amide as fluorogenic substrate preincubated for 50 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM367207(6-(4-fluorophenyl)-2-oxo-N- (4-phenylbutyl)-1,3- b...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells preincubated for 30 mins followed by fluorogenic probe addition and measured after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511269(CHEMBL4550439)
Affinity DataIC50: 80nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511272(CHEMBL4454206)
Affinity DataIC50: 89nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511287(CHEMBL4540417)
Affinity DataIC50: 92nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511291(CHEMBL4476617)
Affinity DataIC50: 92nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511267(CHEMBL4474218)
Affinity DataIC50: 94nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511301(CHEMBL4590615)
Affinity DataIC50: 94nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511277(CHEMBL4584283)
Affinity DataIC50: 95nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511285(CHEMBL4455260)
Affinity DataIC50: 105nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511299(CHEMBL4515811)
Affinity DataIC50: 116nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511266(CHEMBL4522065)
Affinity DataIC50: 120nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511293(CHEMBL4560335)
Affinity DataIC50: 127nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511270(CHEMBL4534076)
Affinity DataIC50: 129nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511292(CHEMBL4443783)
Affinity DataIC50: 134nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511286(CHEMBL4571748)
Affinity DataIC50: 160nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511298(CHEMBL4451058)
Affinity DataIC50: 166nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511260(CHEMBL4587060)
Affinity DataIC50: 192nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511264(CHEMBL4475836)
Affinity DataIC50: 211nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511274(CHEMBL4439693)
Affinity DataIC50: 215nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511283(CHEMBL4545769)
Affinity DataIC50: 247nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511263(CHEMBL4448689)
Affinity DataIC50: 293nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511295(CHEMBL4514724)
Affinity DataIC50: 295nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511284(CHEMBL4459931)
Affinity DataIC50: 340nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511268(CHEMBL4450809)
Affinity DataIC50: 363nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511261(CHEMBL4460936)
Affinity DataIC50: 396nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511289(CHEMBL4451320)
Affinity DataIC50: 436nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511297(CHEMBL4543388)
Affinity DataIC50: 516nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511278(CHEMBL4535309)
Affinity DataIC50: 535nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511279(CHEMBL4461823)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511275(CHEMBL4440226)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511262(CHEMBL4450764)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511294(CHEMBL4561059)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511296(CHEMBL4567125)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511281(CHEMBL4544559)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511288(CHEMBL4440118)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50511298(CHEMBL4451058)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human NAAA expressed in HEK293 cells using PAMCA as fluorogenic substrate preincubated for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed