Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50011824
TargetEpidermal growth factor receptor(Human)
The Research Institute of The Mcgill University Health Center/Glen Hospital

Curated by ChEMBL
LigandPNGBDBM50160900(N*4*-(3-Bromo-phenyl)-N*6*-(2-chloro-ethyl)-quinaz...)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 8 mins in presence of ATP by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
The Research Institute of The Mcgill University Health Center/Glen Hospital

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 31nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 8 mins in presence of ATP by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
The Research Institute of The Mcgill University Health Center/Glen Hospital

Curated by ChEMBL
LigandPNGBDBM50551506(CHEMBL4765122)
Affinity DataIC50: 504nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 8 mins in presence of ATP by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
The Research Institute of The Mcgill University Health Center/Glen Hospital

Curated by ChEMBL
LigandPNGBDBM50551505(CHEMBL4757104)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 8 mins in presence of ATP by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed