Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50011151
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM339679(US10202339, Compound 124)
Affinity DataIC50: 60nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50400272(CHEMBL2180727)
Affinity DataIC50: 170nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50503251(AG-221 | Ag 221 | CC-90007 Free Base | Enasidenib ...)
Affinity DataIC50: 310nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50400272(CHEMBL2180727)
Affinity DataIC50: 390nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545295(CHEMBL4643441)
Affinity DataIC50: 650nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545294(CHEMBL4646777)
Affinity DataIC50: 730nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545296(CHEMBL4639434)
Affinity DataIC50: 960nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50503251(AG-221 | Ag 221 | CC-90007 Free Base | Enasidenib ...)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of IDH2 R172K mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545304(CHEMBL4642948)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545293(CHEMBL4634103)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545293(CHEMBL4634103)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545306(CHEMBL4639321)
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545308(CHEMBL4645603)
Affinity DataIC50: 4.34E+3nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545303(CHEMBL4643550)
Affinity DataIC50: 4.94E+3nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545310(CHEMBL4647101)
Affinity DataIC50: 5.41E+3nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545307(CHEMBL4634280)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM339679(US10202339, Compound 124)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of IDH2 R172K mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545309(CHEMBL4645600)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545305(CHEMBL4632448)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545300(CHEMBL4646635)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545297(CHEMBL4645502)
Affinity DataIC50: 4.69E+4nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545296(CHEMBL4639434)
Affinity DataIC50: 5.18E+4nMAssay Description:Inhibition of IDH2 R172K mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545294(CHEMBL4646777)
Affinity DataIC50: 7.88E+4nMAssay Description:Inhibition of IDH2 R172K mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545298(CHEMBL4638721)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545298(CHEMBL4638721)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545299(CHEMBL4636814)
Affinity DataIC50: 9.79E+4nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50400272(CHEMBL2180727)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM339679(US10202339, Compound 124)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545294(CHEMBL4646777)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545295(CHEMBL4643441)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type IDH1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545296(CHEMBL4639434)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type IDH1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50400272(CHEMBL2180727)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type IDH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM339679(US10202339, Compound 124)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type IDH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50503251(AG-221 | Ag 221 | CC-90007 Free Base | Enasidenib ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type IDH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50503251(AG-221 | Ag 221 | CC-90007 Free Base | Enasidenib ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type IDH1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545293(CHEMBL4634103)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH2 R172K mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545295(CHEMBL4643441)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH2 R172K mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50400272(CHEMBL2180727)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH2 R172K mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545293(CHEMBL4634103)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545293(CHEMBL4634103)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type IDH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM339679(US10202339, Compound 124)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50503251(AG-221 | Ag 221 | CC-90007 Free Base | Enasidenib ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545295(CHEMBL4643441)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545296(CHEMBL4639434)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50400272(CHEMBL2180727)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type IDH1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM339679(US10202339, Compound 124)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type IDH1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545296(CHEMBL4639434)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type IDH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545301(CHEMBL4635443)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545302(CHEMBL4632742)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545293(CHEMBL4634103)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type IDH1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
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