Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50011146
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50289303(5-(4-Methanesulfonyl-phenyl)-6-phenyl-imidazo[2,1-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human COX2 expressed in CHO cells assessed as reduction in arachidonic acid-stimulated PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 40nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545263(CHEMBL4647794)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545264(CHEMBL4643407)
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545262(CHEMBL4639025)
Affinity DataIC50: 58nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545273(CHEMBL4648342)
Affinity DataIC50: 60nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545272(CHEMBL4641524)
Affinity DataIC50: 60nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545271(CHEMBL4635616)
Affinity DataIC50: 60nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545274(CHEMBL4635572)
Affinity DataIC50: 60nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545265(CHEMBL4642268)
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545260(CHEMBL4644150)
Affinity DataIC50: 69nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545270(CHEMBL4639368)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545261(CHEMBL4648858)
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545266(CHEMBL4640385)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545267(CHEMBL4637009)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545257(CHEMBL4633586)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545258(CHEMBL4649049)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545268(CHEMBL4634111)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545256(CHEMBL4633930)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545269(CHEMBL4641800)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545259(CHEMBL4637840)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50174201(ARTHROTEC | GP 45840 | SOLARAZE | Sodium; [2-(2,6-...)
Affinity DataIC50: 840nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50174201(ARTHROTEC | GP 45840 | SOLARAZE | Sodium; [2-(2,6-...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545256(CHEMBL4633930)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545257(CHEMBL4633586)
Affinity DataIC50: 5.33E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545268(CHEMBL4634111)
Affinity DataIC50: 5.97E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545259(CHEMBL4637840)
Affinity DataIC50: 6.23E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545258(CHEMBL4649049)
Affinity DataIC50: 7.11E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545266(CHEMBL4640385)
Affinity DataIC50: 8.14E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545267(CHEMBL4637009)
Affinity DataIC50: 9.84E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545265(CHEMBL4642268)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545261(CHEMBL4648858)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545260(CHEMBL4644150)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545262(CHEMBL4639025)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545264(CHEMBL4643407)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545263(CHEMBL4647794)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Assiut University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50289303(5-(4-Methanesulfonyl-phenyl)-6-phenyl-imidazo[2,1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human COX1 expressed in CHO cells assessed as reduction in arachidonic acid-stimulated PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed