Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50011819
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM18161(DHT | Dihydrotestosterone | [3H]DHT | (5alpha,17be...)
Affinity DataIC50: 18nMAssay Description:Displacement of fluormone-AL green from GST-tagged androgen receptor LBD (unknown origin) measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at androgen receptor in human LNCaP cells transfected with ARR2 PB-eGFP assessed as inhibition of DHT-induced transcriptional act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProstate-specific antigen(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 130nMAssay Description:Inhibition of prostate specific antigen in human LNCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50551469(CHEMBL4760141)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at androgen receptor in human LNCaP cells transfected with ARR2 PB-eGFP assessed as inhibition of DHT-induced transcriptional act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50551468(CHEMBL4798606)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at androgen receptor in human LNCaP cells transfected with ARR2 PB-eGFP assessed as inhibition of DHT-induced transcriptional act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProstate-specific antigen(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50551469(CHEMBL4760141)
Affinity DataIC50: 430nMAssay Description:Inhibition of prostate specific antigen in human LNCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50551470(CHEMBL4790160)
Affinity DataIC50: 820nMAssay Description:Antagonist activity at androgen receptor in human LNCaP cells transfected with ARR2 PB-eGFP assessed as inhibition of DHT-induced transcriptional act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProstate-specific antigen(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50551467(CHEMBL4797715)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of prostate specific antigen in human LNCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50551471(CHEMBL4796332)
Affinity DataIC50: 1.92E+3nMAssay Description:Antagonist activity at androgen receptor in human LNCaP cells transfected with ARR2 PB-eGFP assessed as inhibition of DHT-induced transcriptional act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50551467(CHEMBL4797715)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at androgen receptor in human LNCaP cells transfected with ARR2 PB-eGFP assessed as inhibition of DHT-induced transcriptional act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 3.97E+3nMAssay Description:Displacement of fluormone-AL green from GST-tagged androgen receptor LBD (unknown origin) measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50551467(CHEMBL4797715)
Affinity DataIC50: 4.02E+3nMAssay Description:Displacement of fluormone-AL green from GST-tagged androgen receptor LBD (unknown origin) measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50551473(CHEMBL4759623)
Affinity DataIC50: 5.60E+3nMAssay Description:Antagonist activity at androgen receptor in human LNCaP cells transfected with ARR2 PB-eGFP assessed as inhibition of DHT-induced transcriptional act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50551474(CHEMBL4782786)
Affinity DataIC50: 7.45E+3nMAssay Description:Antagonist activity at androgen receptor in human LNCaP cells transfected with ARR2 PB-eGFP assessed as inhibition of DHT-induced transcriptional act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50551472(CHEMBL4798254)
Affinity DataIC50: 2.04E+4nMAssay Description:Antagonist activity at androgen receptor in human LNCaP cells transfected with ARR2 PB-eGFP assessed as inhibition of DHT-induced transcriptional act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed