Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50011816
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50551404(CHEMBL4764846)
Affinity DataKd:  1.90nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor stably transfected in HEK-293T cells membrane incubated for 9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50215536(CHEBI:73337 | (R)-Alpha-Methylhistamine | CHEMBL26...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human H3 receptor expressed in HEK293 cells preincubated for 30 mins followed by [35S]-GTPgammaS addition and measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human H3 receptor stably transfected in CHO-DUKX cells assessed as increase in cAMP accumulation by measuring reduction in forsko...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human H3 receptor expressed in CHO cells assessed as increase in cAMP accumulation by measuring reduction in forskolin level incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50483134(CHEBI:64156 | Imetit)
Affinity DataEC50:  2.90nMAssay Description:Agonist activity at human H3 receptor expressed in CHO cells assessed as increase in cAMP accumulation by measuring reduction in forskolin level incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50247053(Tiprolisant | 1-(3-(3-(4-chlorophenyl)propoxy)prop...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor stably transfected in HEK-293T cells membrane incubated for 9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50405120(CHEMBL4166098)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor stably transfected in HEK-293T cells membrane incubated for 9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed