Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50008457
TargetToll-like receptor 4(Human)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50177125(ethyl 6-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cycl...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human TLR4 expressed in HEK-Blue cells assessed as decrease in LPS-induced TLR4 response incubated for 1 hr followed by LPS stimulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50519460(CHEMBL4450337)
Affinity DataIC50: 334nMAssay Description:Inhibition of human TLR4 expressed in HEK-Blue cells assessed as decrease in LPS-induced TLR4 response incubated for 1 hr followed by LPS stimulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50519461(CHEMBL4538376)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of human TLR4 expressed in HEK-Blue cells assessed as decrease in LPS-induced TLR4 response incubated for 1 hr followed by LPS stimulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50519459(CHEMBL4568204)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human TLR4 expressed in HEK-Blue cells assessed as decrease in LPS-induced TLR4 response incubated for 1 hr followed by LPS stimulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50519462(CHEMBL4436615)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human TLR4 expressed in HEK-Blue cells assessed as decrease in LPS-induced TLR4 response incubated for 1 hr followed by LPS stimulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed