Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50011115
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545020(Taladegib | LY-2940680 | LY2940680)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50: 13nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545021(CHEMBL4632598)
Affinity DataIC50: 34nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545030(CHEMBL4644288)
Affinity DataIC50: 123nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545025(CHEMBL4635021)
Affinity DataIC50: 285nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545013(CHEMBL4639888)
Affinity DataIC50: 309nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545014(CHEMBL4632537)
Affinity DataIC50: 562nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545024(CHEMBL4645447)
Affinity DataIC50: 754nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545017(CHEMBL4641704)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545018(CHEMBL4646599)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545016(CHEMBL4644469)
Affinity DataIC50: 4.37E+3nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545028(CHEMBL4647112)
Affinity DataIC50: 4.86E+3nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545022(CHEMBL4632758)
Affinity DataIC50: 6.86E+3nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545033(CHEMBL4649551)
Affinity DataIC50: 7.12E+3nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545023(CHEMBL4633504)
Affinity DataIC50: 9.37E+3nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545026(CHEMBL4642236)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545027(CHEMBL4648312)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545029(CHEMBL4642779)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545019(CHEMBL4646912)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545031(CHEMBL4639086)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545032(CHEMBL4639103)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545015(CHEMBL4641820)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed