Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50013259
TargetAurora kinase A(Mouse)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant mouse GST-tagged Aurora A expressed in insect Sf9 cells using Biotin-GLRRASLG as substrate in presence of [gamma33P]ATP by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50277584(N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50277584(N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 18nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50564151(CHEMBL4785479)
Affinity DataIC50: 22nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM12985(CHEMBL402548 | N-{5-[(2R)-2-methoxy-2-phenylacetyl...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 26nMAssay Description:Inhibition of Aurora B (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50564152(CHEMBL4794556)
Affinity DataIC50: 27nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAurora kinase B(Mouse)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataIC50: 172nMAssay Description:Inhibition of recombinant mouse GST-tagged Aurora B expressed in insect Sf9 cells using Biotin-TKQTARKSTGGKAPR as substrate in presence of [gamma33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50564151(CHEMBL4785479)
Affinity DataIC50: 273nMAssay Description:Inhibition of Aurora B (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50277584(N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-...)
Affinity DataIC50: 294nMAssay Description:Inhibition of Aurora B (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50564152(CHEMBL4794556)
Affinity DataIC50: 330nMAssay Description:Inhibition of Aurora B (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50277584(N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-...)
Affinity DataIC50: 350nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed