Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50010707
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541356BDBM50541356(CHEMBL4632678)
Affinity DataIC50: 55nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 2 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541360BDBM50541360(CHEMBL4640859)
Affinity DataIC50: 75nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 2 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541355BDBM50541355(CHEMBL4644850)
Affinity DataIC50: 85nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 2 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541358BDBM50541358(CHEMBL4642007)
Affinity DataIC50: 102nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 2 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088504BDBM50088504(CHEBI:45409 | A-84538 | ABBOTT-84538 | Norvir | Ri...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 20 mins in presence of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541357BDBM50541357(CHEMBL4648061)
Affinity DataIC50: 173nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 2 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541362BDBM50541362(CHEMBL4642617)
Affinity DataIC50: 218nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 2 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541361BDBM50541361(CHEMBL4639605)
Affinity DataIC50: 244nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 2 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541365BDBM50541365(CHEMBL4644634)
Affinity DataIC50: 310nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 20 mins in presence of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541364BDBM50541364(CHEMBL4635548)
Affinity DataIC50: 310nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 20 mins in presence of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541363BDBM50541363(CHEMBL4639033)
Affinity DataIC50: 310nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 20 mins in presence of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541366BDBM50541366(CHEMBL4645102)
Affinity DataIC50: 310nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 20 mins in presence of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541354BDBM50541354(CHEMBL4638454)
Affinity DataIC50: 320nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 2 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541359BDBM50541359(CHEMBL4644724)
Affinity DataIC50: 356nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 2 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541354BDBM50541354(CHEMBL4638454)
Affinity DataIC50: 430nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 20 mins in presence of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed