Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50011105
TargetSterol O-acyltransferase 1(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50544939(CHEMBL4645000)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human SOAT1-mediated [14C]Cholesterol ester biosynthesis in CHO microsomal fraction after 5 mins in presence of [1-14C]oleoyl-CoA by TL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50544939(CHEMBL4645000)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human SOAT2-mediated [14C]Cholesterol ester biosynthesis in CHO microsomal fraction after 5 mins in presence of [1-14C]oleoyl-CoA by TL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50544939(CHEMBL4645000)
Affinity DataIC50: 3.28E+4nMAssay Description:Inhibition of human SOAT1 mediated [14C]Cholesterol ester synthesis in CHO cells after 6 hrs in presence of [14C]Oleic acid by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50544939(CHEMBL4645000)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of human SOAT2-mediated [14C]Cholesterol ester synthesis in CHO cells after 6 hrs in presence of [14C]Oleic acid by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50241945(Atractylenolide III | CHEMBL486961)
Affinity DataIC50: 5.51E+4nMAssay Description:Inhibition of human SOAT1-mediated [14C]Cholesterol ester biosynthesis in CHO microsomal fraction after 5 mins in presence of [1-14C]oleoyl-CoA by TL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50241945(Atractylenolide III | CHEMBL486961)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human SOAT2-mediated [14C]Cholesterol ester biosynthesis in CHO microsomal fraction after 5 mins in presence of [1-14C]oleoyl-CoA by TL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50241945(Atractylenolide III | CHEMBL486961)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of human SOAT1 mediated [14C]Cholesterol ester synthesis in CHO cells after 6 hrs in presence of [14C]Oleic acid by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50241945(Atractylenolide III | CHEMBL486961)
Affinity DataIC50: 1.87E+5nMAssay Description:Inhibition of human SOAT2-mediated [14C]Cholesterol ester synthesis in CHO cells after 6 hrs in presence of [14C]Oleic acid by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed