Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50011800
TargetRAC-gamma serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50398379(CHEMBL2177390 | US10550114, Compound GDC-0068 | US...)
Affinity DataIC50: 26nMAssay Description:Inhibition of full length human Akt3 S472D mutant using GRPRTSSFAEGKK as substrate incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRAC-beta serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50398379(CHEMBL2177390 | US10550114, Compound GDC-0068 | US...)
Affinity DataIC50: 32nMAssay Description:Inhibition of full length human Akt2 S474D mutant using GRPRTSSFAEGKK as substrate incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRAC-gamma serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50551223(CHEMBL4745768)
Affinity DataIC50: 45nMAssay Description:Inhibition of full length human Akt3 S472D mutant using GRPRTSSFAEGKK as substrate incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50551222(CHEMBL4787195)
Affinity DataIC50: 95nMAssay Description:Inhibition of full length human Akt3 S472D mutant using GRPRTSSFAEGKK as substrate incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50551226(CHEMBL4793499)
Affinity DataIC50: 101nMAssay Description:Inhibition of full length human Akt3 S472D mutant using GRPRTSSFAEGKK as substrate incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50551224(CHEMBL4757904)
Affinity DataIC50: 129nMAssay Description:Inhibition of full length human Akt3 S472D mutant using GRPRTSSFAEGKK as substrate incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50551225(CHEMBL4781445)
Affinity DataIC50: 137nMAssay Description:Inhibition of full length human Akt3 S472D mutant using GRPRTSSFAEGKK as substrate incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50551224(CHEMBL4757904)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of full length human Akt2 S474D mutant using GRPRTSSFAEGKK as substrate incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50551226(CHEMBL4793499)
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition of full length human Akt2 S474D mutant using GRPRTSSFAEGKK as substrate incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50551225(CHEMBL4781445)
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of full length human Akt2 S474D mutant using GRPRTSSFAEGKK as substrate incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50551223(CHEMBL4745768)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of full length human Akt2 S474D mutant using GRPRTSSFAEGKK as substrate incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50551222(CHEMBL4787195)
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of full length human Akt2 S474D mutant using GRPRTSSFAEGKK as substrate incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed