Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50011798
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 950nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551202(CHEMBL4780052)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50234948(CHEMBL4078429)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551206(CHEMBL4761852)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at EphA2-Fc in human PC3 cells assessed as reduction in ephrin-A1-Fc stimulated EphA2 phosphorylation preincubated for 20 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551203(CHEMBL4756215)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551198(CHEMBL4783384)
Affinity DataIC50: 2.70E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551195(CHEMBL4795158)
Affinity DataIC50: 3.30E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551202(CHEMBL4780052)
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at EphA2-Fc in human PC3 cells assessed as reduction in ephrin-A1-Fc stimulated EphA2 phosphorylation preincubated for 20 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551194(CHEMBL4763613)
Affinity DataIC50: 3.70E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551203(CHEMBL4756215)
Affinity DataIC50: 4.10E+3nMAssay Description:Antagonist activity at EphA2-Fc in human PC3 cells assessed as reduction in ephrin-A1-Fc stimulated EphA2 phosphorylation preincubated for 20 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 5(Rat)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 4.40E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from rat EphA5 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551196(CHEMBL4776034)
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from mouse EphA3 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551200(CHEMBL4746495)
Affinity DataIC50: 5.20E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551207(CHEMBL4742817)
Affinity DataIC50: 5.50E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50234948(CHEMBL4078429)
Affinity DataIC50: 6.40E+3nMAssay Description:Antagonist activity at EphA2-Fc in human PC3 cells assessed as reduction in ephrin-A1-Fc stimulated EphA2 phosphorylation preincubated for 20 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 6.40E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from mouse EphA4 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551205(CHEMBL4776886)
Affinity DataIC50: 7.10E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 8(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 7.70E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from mouse EphA8 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551192(CHEMBL4796089)
Affinity DataIC50: 9.10E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of biotinylated ephrin-B1-Fc from mouse EphB3 Fc preincubated for 1 hr followed by ephrin-B1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551206(CHEMBL4761852)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at EphA2-Fc in human PC3 cells assessed as reduction in ephrin-A1-Fc stimulated EphA2 phosphorylation preincubated for 20 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551197(CHEMBL4750207)
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 1.40E+4nMAssay Description:Displacement of biotinylated ephrin-B1-Fc from mouse EphB2 Fc preincubated for 1 hr followed by ephrin-B1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551204(CHEMBL4762494)
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551191(CHEMBL4744026)
Affinity DataIC50: 1.70E+4nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 6(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 1.80E+4nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from mouse EphA6 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 1(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from human EphA1 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551193(CHEMBL4791118)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 7(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from mouse EphA7 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-B receptor 1(Rat)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of biotinylated ephrin-B1-Fc from rat EphB1 Fc preincubated for 1 hr followed by ephrin-B1-FC addition and measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of biotinylated ephrin-B1-Fc from mouse EphB4 Fc preincubated for 1 hr followed by ephrin-B1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-B receptor 6(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of biotinylated ephrin-B1-Fc from mouse EphB6 Fc preincubated for 1 hr followed by ephrin-B1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551199(CHEMBL4794685)
Affinity DataIC50: 3.80E+4nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataKi:  300nMAssay Description:Competitive inhibition of biotinylated ephrin-A1-Fc binding to EphA2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50234957(CHEMBL3735125)
Affinity DataKi:  400nMAssay Description:Competitive inhibition of biotinylated ephrin-A1-Fc binding to EphA2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50234948(CHEMBL4078429)
Affinity DataKi:  800nMAssay Description:Competitive inhibition of biotinylated ephrin-A1-Fc binding to EphA2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed