Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50009307
TargetLactoylglutathione lyase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50526946(CHEMBL4456920)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50526945(CHEMBL4473806)
Affinity DataKi:  0.960nMAssay Description:Competitive inhibition of human Glyoxalase-1 using GSH and MGO as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50526943(CHEMBL4436073)
Affinity DataKi:  1nMAssay Description:Competitive inhibition of human Glyoxalase-1 using GSH and MGO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLactoylglutathione lyase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human Glyoxalase-1 using GSH and MGO as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLactoylglutathione lyase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataKi:  5nMAssay Description:Inhibition of human erythrocyte Glyoxalase-1 using GSH and MGO as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50526944(CHEMBL4450158)
Affinity DataKi:  7nMAssay Description:Competitive inhibition of human Glyoxalase-1 using GSH and MGO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50526942(CHEMBL4438930)
Affinity DataKi:  10nMAssay Description:Inhibition of human Glyoxalase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50092826(S-(N-4bromophenyl-N-hydroxycarbamoyl)glutathione |...)
Affinity DataKi:  14nMAssay Description:Inhibition of human erythrocyte Glyoxalase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50526948(CHEMBL4559486)
Affinity DataKi:  19nMAssay Description:Competitive inhibition of human Glyoxalase-1 using GSH and MGO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50092824(S-(N-4chlorophenyl-N-hydroxycarbamoyl)glutathione ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human erythrocyte Glyoxalase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Mouse)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50526947(CHEMBL4584432)
Affinity DataKi:  150nMAssay Description:Competitive inhibition of recombinant mouse His-tagged Glyoxalase-1 using GSH and MGO as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50092825(S-(N-phenyl-N-hydroxycarbamoyl)glutathione | CHEMB...)
Affinity DataKi:  160nMAssay Description:Inhibition of human erythrocyte Glyoxalase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50241121(S-p-bromobenzyl glutatione | S-p-bromobenzylglutat...)
Affinity DataKi:  170nMAssay Description:Inhibition of Glyoxalase-1 (unknown origin) using GSH and MGO as substrates preincubated with substrates for 6 mins followed by enzyme addition by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Mouse)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50517464(CHEMBL1234300)
Affinity DataKi:  230nMAssay Description:Competitive inhibition of recombinant mouse His-tagged Glyoxalase-1 using GSH and MGO as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLactoylglutathione lyase(Mouse)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50233538(3beta-hydroxy-11-oxoolean-12-en-30-oic acid | glyc...)
Affinity DataKi:  290nMAssay Description:Inhibition of recombinant mouse Glyoxalase-1 expressed in Escherichia coli BL21 (DE3) pLysS cells using GSH and MGO as substrate by Dixon plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed