Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50011075
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50410509(SJ000143975 | CHEMBL196585)
Affinity DataEC50:  31nMAssay Description:Agonist activity at ERalpha (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544707(CHEBI:72754 | CHEMBL1900054)
Affinity DataEC50:  20nMAssay Description:Agonist activity at ERalpha (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM29608(Diphenylolpropane | Bisphenol A (BPA) | US9688816,...)
Affinity DataEC50:  797nMAssay Description:Agonist activity at ERalpha (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at ERalpha (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544708(CHEBI:34029 | CHEMBL2392656)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at ERalpha (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544709(CHEMBL4646249)
Affinity DataEC50:  109nMAssay Description:Agonist activity at ERalpha (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544710(CHEMBL4642117)
Affinity DataEC50:  15nMAssay Description:Agonist activity at ERalpha (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  0.370nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM29608(Diphenylolpropane | Bisphenol A (BPA) | US9688816,...)
Affinity DataEC50:  757nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544708(CHEBI:34029 | CHEMBL2392656)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 0.670nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544710(CHEMBL4642117)
Affinity DataIC50: 7.40nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544710(CHEMBL4642117)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544707(CHEBI:72754 | CHEMBL1900054)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50410509(SJ000143975 | CHEMBL196585)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544710(CHEMBL4642117)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as inhibition of E2-induced transcriptional activity measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544707(CHEBI:72754 | CHEMBL1900054)
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50410509(SJ000143975 | CHEMBL196585)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544707(CHEBI:72754 | CHEMBL1900054)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as inhibition of E2-induced transcriptional activity measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50410509(SJ000143975 | CHEMBL196585)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as inhibition of E2-induced transcriptional activity measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544709(CHEMBL4646249)
Affinity DataIC50: 97nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544709(CHEMBL4646249)
Affinity DataIC50: 181nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544709(CHEMBL4646249)
Affinity DataIC50: 331nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as inhibition of E2-induced transcriptional activity measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM29608(Diphenylolpropane | Bisphenol A (BPA) | US9688816,...)
Affinity DataIC50: 870nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM29608(Diphenylolpropane | Bisphenol A (BPA) | US9688816,...)
Affinity DataIC50: 904nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544708(CHEBI:34029 | CHEMBL2392656)
Affinity DataIC50: 2.40E+3nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50544708(CHEBI:34029 | CHEMBL2392656)
Affinity DataIC50: 6.16E+3nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed