Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50009512
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50155838((S)-1-((S)-1-(4-phenylbutanoyl)pyrrolidine-2-carbo...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50155838((S)-1-((S)-1-(4-phenylbutanoyl)pyrrolidine-2-carbo...)
Affinity DataIC50: 0.860nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529486(CHEMBL4549821)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529486(CHEMBL4549821)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529477(CHEMBL4470147)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529479(CHEMBL4446414)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50051539(4-Phenyl-1-[2-(pyrrolidine-1-carbonyl)-pyrrolidin-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529474(CHEMBL4528594)
Affinity DataIC50: 91nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529474(CHEMBL4528594)
Affinity DataIC50: 129nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529492(CHEMBL4529226)
Affinity DataIC50: 147nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529487(CHEMBL4465322)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529487(CHEMBL4465322)
Affinity DataIC50: 264nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529478(CHEMBL4536787)
Affinity DataIC50: 269nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529483(CHEMBL4556841)
Affinity DataIC50: 298nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529481(CHEMBL4552659)
Affinity DataIC50: 3.63E+3nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529476(CHEMBL4520974)
Affinity DataIC50: 4.37E+3nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529494(CHEMBL4540171)
Affinity DataIC50: 5.14E+3nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529475(CHEMBL4588059)
Affinity DataIC50: 6.21E+3nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529493(CHEMBL4521222)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529484(CHEMBL4586782)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529491(CHEMBL4520738)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529482(CHEMBL4483620)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529488(CHEMBL4464018)
Affinity DataIC50: 2.72E+4nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529485(CHEMBL4475037)
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529489(CHEMBL4551013)
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529495(CHEMBL4441906)
Affinity DataIC50: 1.54E+5nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529480(CHEMBL4520852)
Affinity DataIC50: 2.05E+5nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50529490(CHEMBL4436952)
Affinity DataIC50: 4.57E+5nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed