Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50007632
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511076(CHEMBL4538289)
Affinity DataEC50: <3.00E+4nMAssay Description:Inhibition of STING in human THP1 cells by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataEC50:  130nMAssay Description:Inhibition of wild type human STING by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511095(CHEMBL4455856)
Affinity DataEC50:  2.22E+4nMAssay Description:Inhibition of STING in human THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511077(CHEMBL4464910)
Affinity DataEC50:  1.79E+4nMAssay Description:Inhibition of STING in human THP1 cells by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511083(CHEMBL4551891)
Affinity DataEC50: <100nMAssay Description:Inhibition of STING in human THP1 cells in presence of PFO by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509398(CHEMBL4438957)
Affinity DataKd:  5nMAssay Description:Binding affinity to wild type human STING (139 to 379 residues) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511094(CHEMBL4464507)
Affinity DataEC50:  2.54E+4nMAssay Description:Inhibition of STING in human THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509401(CHEMBL4449584)
Affinity DataKd:  1.04E+3nMAssay Description:Binding affinity to wild type human STING (139 to 379 residues) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511092(CHEMBL4472356)
Affinity DataEC50:  740nMAssay Description:Inhibition of STING in human THP1 cells by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511091(CHEMBL4461783)
Affinity DataEC50:  1.02E+4nMAssay Description:Inhibition of STING in human THP1 cells by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511082(CHEMBL4454496)
Affinity DataEC50: <3.00E+4nMAssay Description:Inhibition of STING in human THP1 cells by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50214969(Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...)
Affinity DataKd:  1.37E+5nMAssay Description:Binding affinity to mouse STING by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511089(Cridanimod)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to mouse STING by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509049(CHEMBL4440744)
Affinity DataEC50:  3.10E+3nMAssay Description:Inhibition of wild type human STING by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511088(CHEMBL4457089)
Affinity DataEC50:  390nMAssay Description:Inhibition of STING in human THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511087(CHEMBL4461374)
Affinity DataEC50:  1.93E+4nMAssay Description:Inhibition of STING in human THP1 cells in presence of digitonin by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511081(CHEMBL4543093)
Affinity DataEC50:  4.15E+4nMAssay Description:Inhibition of STING in human THP1 cells by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataKd:  3.79nMAssay Description:Binding affinity to wild type human STING (139 to 379 residues) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511077(CHEMBL4464910)
Affinity DataEC50:  141nMAssay Description:Inhibition of STING in human THP1 cells in presence of digitonin by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511078(CHEBI:75934 | AS-1404 | ASA-404 | ASA404 | DMXAA |...)
Affinity DataKd:  130nMAssay Description:Binding affinity to mouse STING by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511079(CHEMBL4467143)
Affinity DataEC50:  9.50E+3nMAssay Description:Inhibition of STING in human THP1 cells in presence of digitonin by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511080(CHEMBL4449197)
Affinity DataKd:  1.61E+3nMAssay Description:Binding affinity to wild type human STING (139 to 379 residues) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50436163(CHEMBL1231573)
Affinity DataKd:  1.21E+3nMAssay Description:Binding affinity to wild type human STING (139 to 379 residues) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509406(CHEMBL4435159)
Affinity DataKd:  2.87E+5nMAssay Description:Binding affinity to wild type human STING (139 to 379 residues) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511086(CHEMBL4558492)
Affinity DataEC50:  5.80E+3nMAssay Description:Inhibition of STING in human THP1 cells in presence of digitonin by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511076(CHEMBL4538289)
Affinity DataEC50: <100nMAssay Description:Inhibition of STING in human THP1 cells in presence of PFO by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511082(CHEMBL4454496)
Affinity DataEC50: <100nMAssay Description:Inhibition of STING in human THP1 cells in presence of PFO by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511083(CHEMBL4551891)
Affinity DataEC50: <3.00E+4nMAssay Description:Inhibition of STING in human THP1 cells by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511084(CHEMBL4444779)
Affinity DataEC50:  1.12E+4nMAssay Description:Inhibition of STING in human THP1 cells by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511084(CHEMBL4444779)
Affinity DataEC50:  399nMAssay Description:Inhibition of STING in human THP1 cells in presence of digitonin by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511085(CHEMBL4590775)
Affinity DataEC50:  4.50E+3nMAssay Description:Inhibition of STING in human THP1 cells by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511085(CHEMBL4590775)
Affinity DataEC50:  190nMAssay Description:Inhibition of STING in human THP1 cells in presence of digitonin by IFN reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511088(CHEMBL4457089)
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type STING (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509049(CHEMBL4440744)
Affinity DataIC50: 20nMAssay Description:Inhibition of wild type human STING by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511093(CHEMBL4522871)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of wild type human STING by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511090(CHEMBL4454490)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [3H]-cGAMP from mouse STING by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511090(CHEMBL4454490)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [3H]-cGAMP from wild type human STING by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511090(CHEMBL4454490)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of STING in human THP1 cells by R232 IRF-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed