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Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50018447
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50608336(CHEMBL517832)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 10 mins by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosinase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosinase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 0.613nMAssay Description:Inhibition of tyrosinase (unknown origin) using DOPA as substrate incubated for 15 min by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50045000(CHEMBL9 | (norfloxacin)1-Ethyl-6-fluoro-4-oxo-7-pi...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosinase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50241367(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-((2S,4R,5...)
Affinity DataIC50: 0.762nMAssay Description:Inhibition of tyrosinase (unknown origin) using DOPA as substrate incubated for 15 min by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosinase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50217942(3-Rhamnoglucosylquercetin | cid_5280805 | CHEMBL22...)
Affinity DataIC50: 0.856nMAssay Description:Inhibition of tyrosinase (unknown origin) using DOPA as substrate incubated for 15 min by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosinase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50378581(NICOTIFLOROSIDE)
Affinity DataIC50: 0.908nMAssay Description:Inhibition of tyrosinase (unknown origin) using DOPA as substrate incubated for 15 min by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50208612(kurarinone | (-)-kurarinone | (2S)-2-(2,4-dihydrox...)
Affinity DataIC50: 0.960nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 10 mins by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50366824(Avelox | MOXIFLOXACIN | Moxifl-oxacin)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50608335(CHEMBL479477)
Affinity DataIC50: 2nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 10 mins by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosinase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 80nMAssay Description:Inhibition of tyrosinase (unknown origin) using DOPA as substrate incubated for 15 min by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50608328(CHEMBL5273922)
Affinity DataIC50: 100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50608332(CHEMBL5274991)
Affinity DataIC50: 100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50608331(CHEMBL5275965)
Affinity DataIC50: 100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50608330(CHEMBL5265787)
Affinity DataIC50: 100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50608329(CHEMBL5273610)
Affinity DataIC50: 100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50608334(CHEMBL5265798)
Affinity DataIC50: 200nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50608333(CHEMBL5270893)
Affinity DataIC50: 200nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50464458(CHEMBL4285973)
Affinity DataIC50: 200nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate pre-incubated for 10 mins followed by substrate addition and measured after 20 mins by mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosinase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM85807(NSC_6054 | CAS_60-12-8 | Beta-PEA)
Affinity DataIC50: 315nMAssay Description:Inhibition of tyrosinase (unknown origin) using DOPA as substrate incubated for 15 min by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosinase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50608337((+)-Anymol | CHEMBL477832)
Affinity DataIC50: 635nMAssay Description:Inhibition of tyrosinase (unknown origin) using DOPA as substrate incubated for 15 min by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed