Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50007627
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511058(CHEMBL4453514)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511056(CHEMBL4578912)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511057(CHEMBL4437587)
Affinity DataIC50: 3.94E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511063(CHEMBL4452349)
Affinity DataIC50: 1.24E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511061(CHEMBL4439676)
Affinity DataIC50: 1.73E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511059(CHEMBL4468115)
Affinity DataIC50: 1.93E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511060(CHEMBL4582859)
Affinity DataIC50: 2.99E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511062(CHEMBL4448917)
Affinity DataIC50: 3.15E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511055(CHEMBL4519402)
Affinity DataIC50: 3.38E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511058(CHEMBL4453514)
Affinity DataKi:  1.10E+4nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and further incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
The University of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511056(CHEMBL4578912)
Affinity DataKi:  1.30E+5nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and further incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed