Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50009503
TargetProteasome subunit beta type-5(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataIC50: 30nMAssay Description:Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-1(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataIC50: 500nMAssay Description:Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-2(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-1(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529337(CHEMBL4461655)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529333(CHEMBL4446535)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529337(CHEMBL4461655)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529333(CHEMBL4446535)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529336(CHEMBL4586314)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529337(CHEMBL4461655)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529336(CHEMBL4586314)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529333(CHEMBL4446535)
Affinity DataIC50: 2.79E+4nMAssay Description:Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529335(CHEMBL4528868)
Affinity DataIC50: 3.01E+4nMAssay Description:Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529335(CHEMBL4528868)
Affinity DataIC50: 3.19E+4nMAssay Description:Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529336(CHEMBL4586314)
Affinity DataIC50: 7.61E+4nMAssay Description:Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529334(CHEMBL4458315)
Affinity DataIC50: 8.73E+4nMAssay Description:Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529334(CHEMBL4458315)
Affinity DataIC50: 9.36E+4nMAssay Description:Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529332(CHEMBL4521474)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529335(CHEMBL4528868)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529334(CHEMBL4458315)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529332(CHEMBL4521474)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Iwate University

Curated by ChEMBL
LigandPNGBDBM50529332(CHEMBL4521474)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed