Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50007620
TargetSodium/glucose cotransporter 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50449244(CHEMBL3125150)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50342885((1S,2S,3S,4R,5S)-5-[4-Chloro-3-(4-ethoxybenzyl)phe...)
Affinity DataIC50: 0.877nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50235017(LP-802034 | LX-4211 | Sotagliflozin)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50315426((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition OF SGLT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50315426((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50396779(TOFOGLIFLOZIN)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50510994(CHEMBL4521016)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50510994(CHEMBL4521016)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human SGLT2 expressed i HEK293 cell membranes assessed as reduction in [14C]-alpha-methyl glucopyranoside uptake incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50386885(CANAGLIFLOZIN HYDRATE | CANAGLIFLOZIN | US10752604...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50381554(CHEMBL2018096)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50235017(LP-802034 | LX-4211 | Sotagliflozin)
Affinity DataIC50: 35nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 1(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50386885(CANAGLIFLOZIN HYDRATE | CANAGLIFLOZIN | US10752604...)
Affinity DataIC50: 684nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50381554(CHEMBL2018096)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50342885((1S,2S,3S,4R,5S)-5-[4-Chloro-3-(4-ethoxybenzyl)phe...)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50315426((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...)
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50510994(CHEMBL4521016)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50396779(TOFOGLIFLOZIN)
Affinity DataIC50: 8.44E+3nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed