Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50009286
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50526855(CHEMBL4580266 | US20240199535, Example 4)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50526854(CHEMBL4562509)
Affinity DataIC50: 103nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50018011(CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE)
Affinity DataIC50: 320nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Blood fluke)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50203188(CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...)
Affinity DataIC50: 430nMAssay Description:Inhibition of Schistosoma mansoni DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50526858(CHEMBL4592233)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of DHODH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50203188(CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50365231(CHEMBL1738786 | US9238653, Table 5, Compound 7)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Blood fluke)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Schistosoma mansoni DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Blood fluke)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50365231(CHEMBL1738786 | US9238653, Table 5, Compound 7)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Schistosoma mansoni DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50526853(CHEMBL4520115)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of DHODH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Blood fluke)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50018011(CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Schistosoma mansoni DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50526856(CHEMBL4469092)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50526857(F901318 | Olorofim)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin (Unito)

Curated by ChEMBL
LigandPNGBDBM50295257((R)-N-(6-chloro-2,3,4,9-tetrahydro-1H-carbazol-1-y...)
Affinity DataKi:  203nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed