Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50006724
TargetSerine/threonine-protein kinase VRK1(Human)
Universidade Estadual De Campinas (Unicamp)

Curated by ChEMBL
LigandPNGBDBM50502749(CHEMBL4435359)
Affinity DataKd:  190nMAssay Description:Binding affinity to recombinant full length N-terminal His-tagged VRK1 (unknown origin) (1 to 396 residues) expressed in Escherichia coli BL 21 DE3-R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase VRK2(Human)
Universidade Estadual De Campinas (Unicamp)

Curated by ChEMBL
LigandPNGBDBM50502750(CHEMBL4467571)
Affinity DataKd:  401nMAssay Description:Binding affinity to recombinant N-terminal His-tagged VRK2 kinase domain (unknown origin) (14 to 335 residues) expressed in Escherichia coli BL 21 DE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase VRK1(Human)
Universidade Estadual De Campinas (Unicamp)

Curated by ChEMBL
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)
Affinity DataIC50: 33nMAssay Description:Inhibition of full length wild-type VRK1 (unknown origin) expressed in insect cells using ULight-Histone 3-Thr3 peptide as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase VRK1(Human)
Universidade Estadual De Campinas (Unicamp)

Curated by ChEMBL
LigandPNGBDBM50502749(CHEMBL4435359)
Affinity DataIC50: 150nMAssay Description:Inhibition of full length wild-type VRK1 (unknown origin) expressed in insect cells using ULight-Histone 3-Thr3 peptide as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase VRK1(Human)
Universidade Estadual De Campinas (Unicamp)

Curated by ChEMBL
LigandPNGBDBM50502748(CHEMBL4436323)
Affinity DataIC50: 260nMAssay Description:Inhibition of full length wild-type VRK1 (unknown origin) expressed in insect cells using ULight-Histone 3-Thr3 peptide as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase VRK1(Human)
Universidade Estadual De Campinas (Unicamp)

Curated by ChEMBL
LigandPNGBDBM50502751(CHEMBL4452098)
Affinity DataIC50: 674nMAssay Description:Inhibition of full length wild-type VRK1 (unknown origin) expressed in insect cells using ULight-Histone 3-Thr3 peptide as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed