Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50008115
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50515758(CHEMBL4453575)
Affinity DataIC50: 10nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50515763(CHEMBL4458303)
Affinity DataIC50: 20nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50515758(CHEMBL4453575)
Affinity DataKi:  92nMAssay Description:Inhibition of human dihydrofolate reductase assessed as inhibition constant by UV-Vis spectra based Benesi Hilebrand equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50515761(CHEMBL4533705)
Affinity DataIC50: 100nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50515760(CHEMBL4544130)
Affinity DataIC50: 210nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50515762(CHEMBL4581410)
Affinity DataIC50: 670nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM66082(SMR000449324 | MLS001401431 | (2S)-2-[[4-[[2,4-bis...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50515763(CHEMBL4458303)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human dihydrofolate reductase assessed as inhibition constant by UV-Vis spectra based Benesi Hilebrand equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50515759(CHEMBL4467394)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed