Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50008430
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519299(CHEMBL4536230)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519299(CHEMBL4536230)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519305(CHEMBL4449427)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519303(CHEMBL4590955)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519301(CHEMBL4439045)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519302(CHEMBL4553357)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519304(CHEMBL4440677)
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human U2OS cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human HeLa cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human MDA-MB-231 cells co-transfected with FLAG-tagged p53 assessed as reduction in p53...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of V5-tagged SMYD2 (unknown origin) transfected in HEK293 cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 methylati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human MCF7 cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human CAL120 cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519303(CHEMBL4590955)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519302(CHEMBL4553357)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519305(CHEMBL4449427)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519301(CHEMBL4439045)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)