Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50008782
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 22nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 136nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM25150(Belinostat | (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)...)
Affinity DataIC50: 189nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522146(CHEMBL4469317)
Affinity DataIC50: 195nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522150(CHEMBL4466520)
Affinity DataIC50: 235nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522151(CHEMBL4571280)
Affinity DataIC50: 258nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522148(CHEMBL4454331)
Affinity DataIC50: 278nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522145(CHEMBL4463774)
Affinity DataIC50: 292nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522149(CHEMBL4516302)
Affinity DataIC50: 296nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522142(CHEMBL566831)
Affinity DataIC50: 370nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522144(CHEMBL4466864)
Affinity DataIC50: 371nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522146(CHEMBL4469317)
Affinity DataIC50: 381nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522143(CHEMBL4518387)
Affinity DataIC50: 415nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522147(CHEMBL4573804)
Affinity DataIC50: 420nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522151(CHEMBL4571280)
Affinity DataIC50: 449nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522147(CHEMBL4573804)
Affinity DataIC50: 463nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522149(CHEMBL4516302)
Affinity DataIC50: 602nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522148(CHEMBL4454331)
Affinity DataIC50: 610nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522145(CHEMBL4463774)
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522150(CHEMBL4466520)
Affinity DataIC50: 636nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522147(CHEMBL4573804)
Affinity DataIC50: 819nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522143(CHEMBL4518387)
Affinity DataIC50: 837nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522146(CHEMBL4469317)
Affinity DataIC50: 926nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522149(CHEMBL4516302)
Affinity DataIC50: 950nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522151(CHEMBL4571280)
Affinity DataIC50: 994nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522150(CHEMBL4466520)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522144(CHEMBL4466864)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522143(CHEMBL4518387)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522148(CHEMBL4454331)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522145(CHEMBL4463774)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522144(CHEMBL4466864)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed