Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50009412
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50528604(CHEMBL4445335)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant full length human CDK4/Cyclin D3 using Rb-fragmen as substrate incubated for 40 mins by [gamma-33P]-ATP based radiometric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50528604(CHEMBL4445335)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human VEGFR2 (790 to end residues) using myelin ba as substrate incubated for 40 mins by [gamma-33P]-ATP based radiometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50528604(CHEMBL4445335)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human full length CDK2/CyclinA using as histone H1 substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50528604(CHEMBL4445335)
Affinity DataIC50: 247nMAssay Description:Inhibition of recombinant human full length CDK1/CyclinB using histone H1 as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed