Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50010170
TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50535759(CHEMBL4471843 | US12227515, Compound 3)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human His-6-tagged PTP4A3 expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM396097(US10308663, JMS-631-053 | US12227515, Compound JMS...)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human His-6-tagged PTP4A3 expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM396097(US10308663, JMS-631-053 | US12227515, Compound JMS...)
Affinity DataIC50: 50nMAssay Description:Inhibition of PTP4A1 (unknown origin) expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM396097(US10308663, JMS-631-053 | US12227515, Compound JMS...)
Affinity DataIC50: 52nMAssay Description:Inhibition of PTP4A2 (unknown origin) expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human His-6-tagged PTP4A3 expressed in Escherichia coli assessed as increase in polarization using TAMRAThr-Ala-Asp-Ile-Tyr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human His-6-tagged PTP4A1 expressed in Escherichia coli assessed as increase in polarization using TAMRAThr-Ala-Asp-Ile-Tyr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human His-6-tagged PTP4A2 expressed in Escherichia coli assessed as increase in polarization using TAMRAThr-Ala-Asp-Ile-Tyr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarbox...)
Affinity DataIC50: 300nMAssay Description:Inhibition of PTP4A1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarbox...)
Affinity DataIC50: 300nMAssay Description:Inhibition of PTP4A3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarbox...)
Affinity DataIC50: 300nMAssay Description:Inhibition of PTP4A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50237949(2-(5-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)...)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of recombinant human PTP4A3 expressed in Escherichia coli BL21 (DE3) assessed as reduction in hydrolysis using DIFMUP as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50535760(CHEMBL4466901)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of recombinant human PTP4A3 expressed in Escherichia coli BL21 (DE3) assessed as reduction in hydrolysis using DIFMUP as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50237948((E)-2-(2-(5-(4-chlorophenyl)furan-2-yl)vinyl)-6-me...)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant human PTP4A3 expressed in Escherichia coli BL21 (DE3) assessed as reduction in hydrolysis using DIFMUP as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50535761(CHEMBL4539375)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PTP4A1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM396097(US10308663, JMS-631-053 | US12227515, Compound JMS...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human PTP1B assessed as reduction in hydrolysis using DIFMUP as substrate incubated for 30 mins in presence of DTT by Fluorescence base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed