Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50008187
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516619(CHEMBL4547542)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of human recombinant BRAF V600E mutant using MEK1 as substrate measured after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50484216(CHEMBL1822256)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant BRAF V600E mutant using MEK1 as substrate measured after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516609(CHEMBL4445595)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516607(CHEMBL4530882)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516620(CHEMBL4557039)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516612(CHEMBL4527473)
Affinity DataIC50: 157nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516611(CHEMBL4586188)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516608(CHEMBL4539692)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516618(CHEMBL4546383)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516613(CHEMBL4441288)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516605(CHEMBL4519570)
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516615(CHEMBL4571674)
Affinity DataIC50: 540nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516617(CHEMBL4448871)
Affinity DataIC50: 660nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516606(CHEMBL4470156)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516616(CHEMBL4588836)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516610(CHEMBL4435526)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516614(CHEMBL4459079)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed