Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50010156
TargetProprotein convertase subtilisin/kexin type 9(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50535693(CHEMBL4572783)
Affinity DataIC50: 202nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 24 hrs followed by medium replenishment and measured after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50535683(CHEMBL4549362)
Affinity DataIC50: 250nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50535686(CHEMBL4562557)
Affinity DataIC50: 300nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50535688(CHEMBL4585306)
Affinity DataIC50: 900nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50535690(CHEMBL4528279)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50535687(CHEMBL4435394)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50535689(CHEMBL4462933)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50535685(CHEMBL4531399)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50535691(CHEMBL4461546)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50535692(CHEMBL4545753)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50535684(CHEMBL4446521)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049059(CHEMBL3319503 | US9969686, Compound 10a | US107308...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed